本刊主编、博士后、留美华侨科学家饶绍奇的个人简历.doc 7页

本刊主编、博士后、留美华侨科学家饶绍奇的个人简历饶绍奇(博士)美国克利夫兰临床基金组织，心血管病遗传学中心美国克利夫兰临床基金组织,分子心脏病学系邮编：俄亥俄州44195传真：(216)444-2682电话：(216)445-0056(办公室)(216)561-2752(家)电子信箱：raos@ccf.org或paulsrrao@yahoo.com.cn能力概括具有深厚的生物学、遗传学、统计学和计算数学知识和专业背景14+年高等教育和训练19+年在学术界、工业和资讯的工作经验教育(学历)硕士(第二博士肄业)，2001，生物统计学及遗传流行病学(医学)，凯斯西部储备大学博士，1997，遗传学，弗吉尼亚州立理工大学硕士，1986，动物遗传育种，北京农业大学学士，1983，动物学，新疆八一农学院部分课程数据采矿随机过程生物信息学与分子进化论高级统计理论I，II统计学理论I，II线型模型理论线型模型混合线型模型广义线型模型Bayes统计学方差组分应用统计学I，II时间序列分析应用多元统计学数据分析遗传学计算方法生物统计学BASIC及编程设计统计遗传学专题人类遗传学统计方法遗传学统计模型数量遗传学I，II群体遗传学I，II流行病学连锁分析组织胚胎学生理学无机化学有机化学生物化学计量化学分子生物学分子生物学试验技术营养学2工作经历 2001.7-:项目科学家(助理教授)1998.6-2001.7:研究及教学助理，凯斯西部储备大学1997.4-1998.4:博士后研究员，加利福尼亚大学河滨分校1993.8-1997.1:教学助理，弗吉尼亚州立理工大学1988.11-1993.6:助理研究员，北京农林科学院1986.7-1988.11:研究助理，北京农林科学院计算机技能数学及统计软件：SAS，Splus，Mathematica和MATLAB等编程语言：Fortran77，BASIC，C和C++，Perl等文字处理和图像：MiscrosoftWord，WordPerfect，Freelance，SigmaPlot，Excel,Powerpoint,Photoshop,EndNote等数据库软件：DBASE，FOXBASE和COBOL操作系统：UNIX，LINUX,IBMmainframes(1090和3084))，VMX/VAX11/785，MSWindows和DOS等遗传学软件：SAGE，GeneHunter,MTDFREML，DFREML,PEST，ZPLAN，ODCE和LSML76等生物信息学软件：BLAST/FASTA,DNAstar,VNTIsuit,Rasmol,GeneSpring,Phylip等近五年来主要论著目录(2004-1998)1.QWang,SRao*,GShen,LLi,KNewby,WJRoger,RCannata,EZirzow,RCElston,EJTopol:Prematuremyocardialinfarctionnovelsusceptibilitylocusonchromosome1p34-36identifiedbygenome-widelinkageanalysis.AmericanJournalofHumanGenetics2004,*asaco-firstauthor:(inpress,willappearnextFebruary).2.Q-JWang,C-YLu,NLi,SRao,Y-BShi,D-YHan,XLi,J-YCao,L-MYu,M-XGuan,etal:Y-linkedinheritanceofnon-syndromichearingimpairmentinalargeChinesefamily.JMedGenet2004:(inpress).3.XTian,MLiu,RKadaba,AATimur,LYang,S-AYou,QChen,PSzafranski,SRao,DEHousman,etal:Positionalcloningofanovelangiogenicfactorgene:VG5QmutationsareassociatedwithKlippel-Trenaunarysyndrome.Nature2004:(inpress).4.JJMcCarthy,AParker,DJMoliterno,RSalem,QWang,EFPlow,SRao,G-QShen,WJRogers,LKNewby,etal:Large-scaleassociationanalysisforidentificationofgenesunderlyingcoronaryheartdisease:Cumulativeperspectivefromanalysisof111candidategenes.JournalofMedicalGenetics2004:(inpress).5.XLi,SRao,ZGuo:MATLABandItsApplicationinBio-Medicine.Beijing:ChinaSciencePress;2004.6.XLi,SRao,ZGuo:ProtocolsinMolecularDataAnalysis.Beijing:ChinaSciencePress;2004.7.XLi,SRao,TZhang,ZGuo,KLMoser,EJTopol:AnensemblemethodforgenediscoverybasedonDNAmicroarraydata.ScienceinChina(C)2004:(inpress).8.XLi,TZhang,SRao,LLi:Adecisionforestforextractingfeaturegenes.JournalofHarbinInstituteofTechnology2004:(inpress).9.SAYou,SRArchacki,GAngheloiu,CSMoravec,SRao,MKinter,EJTopol,QWang:Proteomic approachtocoronaryatherosclerosisshowsferritinlightchainasasignificantmarker:evidenceconsistentwithironhypothesisinatherosclerosis.PhysiolGenomics2003,13:25-30.10.SRao,LLi,XLi,KLMoser,ZGuo,GShen,RCannata,EZirzow,EJTopol,QWang:Geneticlinkageanalysisoflongitudinalhypertensionphenotypesusingthreesummarymeasures.BMCGenetics2003,Suppl4:Article24.11.XLi,SRao,KLMoser,RCElston,JMOlson,ZGuo,TZhang:Sib-pairLinkageAnalysisofComplexDiseasesviaPatternRecognition.In:GeneticsforComplexPolygenicDiseasesandHumanHealthEditedbyH-WDeng,X-SWu,D-ZYin.pp.26-38.Changsa,China:HunanNormalUniversityPress;2003:26-38.312.ZGuo,XLi,SRao,KLMoser,TZhang,BGong,GShen,LLi,RCannata,EZirzow,etal:Multivariatesib-pairlinkageanalysisoflonitudinalphenotypesbythreestepwiseanalysisapproaches.BMCGenetics2003,Suppl4:Article68.13.WJGauderman,SMacgregor,LBriollais,KScurrah,MTobin,TPark,DWang,SRao,SJohn,SBull:Longitudinaldataanalysisinpedigreestudies.GenetEpidemiol2003,Suppl1:S18-S28.14.SRao1,XLi,ZGuo,KLMoser,LLi,EJTopol,QWang:Ananalysis-of-variance(ANOVA)approachforsib-pairlinkageanalysisofcomplexordinalhumandiseases.TheChineseJournalofBiomedicalEngineering,EnglishEdition2002,11:104-112.15.SRao,LLi,XLi,KLMoser,ZGuo,GShen,RCannata,EZirzow,EJTopol,QWang:Comparisonofdifferentsummarymeasures(mean,slope,andprincipalcomponents)forgeneticlinkageanalysisoflongitudinalhypertensivephenotypes.In:GeneticWorkshop13,InternationalGeneticEpidemiologySociety;2002;NewOrleans,LA,USA.128-132.16.XLi,SRao,KLMoser,RCElston,JMOlson,ZGuo,TZhang:Geneticmappingofcomplexdiscretehumandiseasesbydiscriminantanalysis.ProgressInNaturalScience2002,12:431-437.17.ZGuo,XLi,SRao,KLMoser,BGong,GShen,LLi,RCannata,EZirzow,EJTopol,etal:Discriminantsib-pairlinkageanalysisoflongitudinalphenotypes.In:GeneticWorkshop13,InternationalGeneticEpidemiologySociety;2002;NewOrleans,LA,USA.357-361.18.DWang,SRao,Q-PZhang,XLi:Evaluationofadouble-deckcagedesignforbroilerbreeders.AnimalScience&VeterinaryMedicine2001,18:67-70.19.SRao1,Q-PZhang,XLi,ZGuo:Mappingquantitativetraitloci(QTLs)ofordinaltraitsusingastructuralheteroskedasticthresholdmodel:IINumericalApplication.MathematicaApplicata2001,14:125-132.20.SRao,JMOlson,KLMoser,CGray-McGuire,GRBruner,JKelly,JBHarley:Linkageanalysisofhumansystemiclupuserythematosus-relatedtraits:aprincipalcomponentapproach.ArthritisRheum2001,44:2807-2818.21.SRao,XLi,ZGuo,Q-PZhang:Mappingquantitativetraitloci(QTLs)ofordinaltraitsusingastructuralheteroskedasticthresholdmodel:ITheory.MathematicaApplicata2001,14:46-51.22.GPardo,SRao,JMOlson,KLMoser,CGray-McGuire,GRBruner,JKelly,JBHarley:Possiblegeneticlinkageswithneuropsychiatricmanifestationsofsystemiclupuserythematosus. Neurology2001,56:A132-133.23.XLi,SRao,RCElston,JMOlson,KLMoser,TZhang,ZGuo:Locatingthegenesunderlyingasimulatedcomplexdiseasebydiscriminantanalysis.GenetEpidemiol2001,21Suppl1:S516-21.24.ZGuo,XLi,SRao:AnalysisofMedicalData:AnIntroductiontoBioinformatics.Harbin,China:HarbinPublisher;2001.25.SRao,XLi:Strategiesforgeneticmappingofcategoricaltraits.Genetica2000,109:183-97.26.SRao,DRNotter:GeneticanalysisoflittersizeinTarghee,Suffolk,andPolypaysheep.JAnimSci2000,78:2113-20.27.JMOlson,SRao,KJacobs,RCElston:Linkageofchromosome1markerstoalcoholism-relatedphenotypesbysibpairlinkageanalysisofprincipalcomponents.GenetEpidemiol1999,17Suppl1:S271-6.28.SRao,SXu:Mappingquantitativetraitlocifororderedcategoricaltraitsinfour-waycrosses.Heredity1998,81(Pt2):214-24.近五年来主要摘要(SCI及其它数据库收录)目录(2003-1998)1.QWang,SRao,GShen,LLi,KNewby,WJRoger,RCannata,EZirzow,RCElston,EJTopol:Genome-widelinkageanalysisidentifiesnovelsusceptibilitylociforprematuremyocardialinfarction.GenetEpidemiol2003,25:277.2.QWang,SRao,GShen,LLi,KNewby,WJRoger,RCannata,EZirzow,RCElston,EJTopol:Prematuremyocardialinfarctionnovelsusceptibilitylociidentifiedbygenome-widelinkageanalysis.TheAmericanJournalofHumanGenetics2003,73:35.3.EJTopol,SRao,RCElston,QWang:Genome-wideLinkageAnalsysisofFamilial,PrematureMyocardialInfarctionIdentifiesNovelSusceptibilityLoci.Circulation2003,AmericanHeartAssociationScientificSessions2003:IV-49.4.SRao,XLi,T-WZhang,ZGuo,KLMoser,EJTopol,QWang:AnensemblemethodforgenediscoverybasedonDNAmicroarraydata.TheAmericanJournalofHumanGenetics2003,73:604.5.SRao,XLi,TZhang,ZGuo,KLMoser,EJTopol,QWang:Miningdisease-relevantgenesfromDNAmicroarraydatabyanensembledecisionapproach.GenetEpidemiol2003,25:267.46.GShen,SRao,RCannata,EZirzow,ABakos,EJTopol,QWang:Exclusionofchromosome2and14coronaryarterydiseaselociinanAmericanCaucasianpopulation.TheAmericanJournalofHumanGenetics2002,71:A1549.7.SRao,GShen,RCannata,EZirzow,RCElston,XLi,LLi,EFPlow,EJTopol,QWang:Heritabilityandlinkageanalysisofprematurecoronaryarterydiseaseandrelatedtraitsbasedonastudyof428ascertainedmultiplexfamilies.GeneticEpidemiology2002,23:301.8.SRao,GShen,RCannata,EZirzow,RCElston,XLi,EFPlow,EJTopol,QWang:Heritabilityofprematurecoronaryarterydiseaseanditsrelatedtraitsbasedonastudyof428ascertainedmultiplexfamilies.TheAmericanJournalofHumanGenetics2002,71:A1042.9.SRao,ZGuo,XLi:Ananalysis-of-variance(ANOVA)approachforsib-pairlinkageanalysisofcomplexordinalhumandiseases.In:InternationalSymposiumonMappingandIdentificationof GenesforComplexPolygenicTraitsandDiseases;2001;Changsha,China.46.10.XLia,SRao,KLMoser,RCElston,JMOlson,ZGuo,G-HZhu:Geneticmappingofcomplexdiscretehumandiseasesbydiscriminantanalysis.In:InternationalSymposiumonMappingandIdentificationofGenesforComplexPolygenicTraitsandDiseases;2001;Changsha,China.32.11.JBHarley,SRao,KLMoser,CGray-McGuire,JKelly,GRBruner,JMOlson:Principal-componentanalysisandthemappingofhumansystemiclupuserythematosus-relatedtraits.In:TheFederationofClinicalImmunologySocieties(FOCIS)AnnualMeeting;2001;Boston,Massachusetts.12.KLMoser,CGray-McGuire,JKelly,SRao,RSalmon,RPKimberly,JCEdberg,BRNeat,JMOlson,JBHarley:Geneticlinkagestohumansystemiclupuserythematosus.FASEB2000,14:A1210.13.SRao,JMOlson,CGray-McGuire,KLMoser,JBHarley:Linkageanalysisofhumansystemiclupuserythematosusrelatedtraits.TheAmericanJournalofHumanGenetics1999,65:2501.14.SRao,SXu:Multipointgenemappingofquantitativetraitlociforordinaltraitsusingfour-waycrosses.In:Plant&AnimalGenomeVI,InternationalPlant&AnimalGenomeConference;1998;SanDiego,California.P126.近五年来主要会议论文目录(2003-1998)1.QWang,SRao,GShen,LLi,KNewby,WJRoger,RCannata,EZirzow,RCElston,EJTopol:Prematuremyocardialinfarctionnovelsusceptibilitylociidentifiedbygenome-widelinkageanalysis.In:TheAmericanSocietyofHumanGenetics53rdAnnualMeeting;2003;LosAngeles.Aconcurrentinvitedsession.2.QWang,SRao,GShen,LLi,KNewby,WJRoger,RCannata,EZirzow,RCElston,EJTopol:Genome-widelinkageanalysisidentifiesnovelsusceptibilitylociforprematuremyocardialinfarction.In:InternationalGeneticEpidemiologySociety12thAnnualMeeting;2003;RedondoBeach,California,USA.Aposter.3.EJTopol,SRao,RCElston,QWang:Genome-wideLinkageAnalsysisofFamilial,PrematureMyocardialInfarctionIdentifiesNovelSusceptibilityLoci.In:AmericanHeartAssociationScientificSessions2003;2003;Orlando,Florida,USA.Aconcurrentinvitedsession.4.SRao,XLi,T-WZhang,ZGuo,KLMoser,EJTopol,QWang:AnensemblemethodforgenediscoverybasedonDNAmicroarraydata.In:TheAmericanSocietyofHumanGenetics53rdAnnualMeeting;2003;LosAngeles.Aposter.5.SRao,XLi,TZhang,ZGuo,KLMoser,EJTopol,QWang:Miningdisease-relevantgenesfromDNAmicroarraydatabyanensembledecisionapproach.In:InternationalGeneticEpidemiologySociety12thAnnualMeeting;2003;RedondoBeach,California,USA.Theplenarysession.6.GShen,SRao,RCannata,EZirzow,ABakos,EJTopol,QWang:Exclusionofchromosome2and14coronaryarterydiseaselociinanAmericanCaucasianpopulation.In:the52ndAnnualMeetingofASHG;2002;Baltimore,Maryland.Aposter.7.SRao,GShen,RCannata,EZirzow,RCElston,XLi,EFPlow,EJTopol,QWang:Heritabilityofprematurecoronaryarterydiseaseanditsrelatedtraitsbasedonastudyof428ascertainedmultiplexfamilies.In:the52ndAnnualMeetingofASHG;2002;Baltimore,Maryland.Aposter.8.SRao,GShen,RCannata,EZirzow,RCElston,XLi,LLi,EFPlow,EJTopol,QWang:Heritabilityandlinkageanalysisofprematurecoronaryarterydiseaseandrelatedtraitsbased onastudyof428ascertainedmultiplexfamilies.In:the11thAnnualMeeting(IGES2002)ofInternationalGeneticEpidemiologySociety;2002;NewOrleans,Louisiana.Aposter.9.SRao,ZGuo,XLi:Ananalysis-of-variance(ANOVA)approachforsib-pairlinkageanalysisofcomplexordinalhumandiseases.In:InternationalSymposiumonMappingandIdentificationofGenesforComplexPolygenicTraitsandDiseases;2001;Changsha,China.Aposter.10.XLi,SRao,KLMoser,RCElston,JMOlson,ZGuo,G-HZhu:Geneticmappingofcomplexdiscretehumandiseasesbydiscriminantanalysis.In:InternationalSymposiumonMappingand5IdentificationofGenesforComplexPolygenicTraitsandDiseases;2001;Changsha,China.Aninvitedspeaker.11.JBHarley,SRao,KLMoser,CGray-McGuire,JKelly,GRBruner,JMOlson:Principal-componentanalysisandthemappingofhumansystemiclupuserythematosus-relatedtraits.In:TheFederationofClinicalImmunologySocieties(FOCIS)AnnualMeeting;2001;Boston,Massachusetts.Aposter.12.XLi,SRao,RCElston,JMOlson,KLMoser,TZhang,ZGuo:Locatingthegenesunderlyingasimulatedcomplexdiseasebydiscriminantanalysis.In:GeneticWorkshop12,InternationalGeneticEpidemiologySociety;2000;SanAntonio,TX,USA.Aposter.13.JKelly,KLMoser,CGray-McGuire,SRao,RSalmon,RPKimberly,JBHarley:GeneticlinkagestohumanSLEin126multiplexpedigrees.In:2000InternationalGeneticEpidemiologySociety(IGES)Meeting;2000;Antario,Texas,USA.Aposter.14.SRao,JMOlson,CGray-McGuire,KLMoser,JBHarley:Linkageanalysisofhumansystemiclupuserythematosusrelatedtraits.In:AmericanSocietyofHumanGenetics(ASHG)Conference;1999;SanFrancisco.Aposter.15.SRao,SXu:Multipointgenemappingofquantitativetraitlociforordinaltraitsusingfour-waycrosses.In:Plant&AnimalGenomeVI,InternationalPlant&AnimalGenomeConference;1998;SanDiego,California.Aposter.16.JMOlson,SRao,KJacob,RCElston:Linkageofchromosome1markerstoalcoholism-relatedphenotypesbysib-pairlinkageanalysisofprincipalcomponents.In:GeneticAnalysisWorshop12,TheInternationalGeneticEpidemiologySociety,SponsoredbyTheNationalInstituteofHealth;1998;Paris,France.Aposter.科研资助情况(在研项目)1)人类复杂疾病基因表达谱特征基因识别技术：中国国家自然科学基金2003年项目(30370798,01/2004-12/2006)。主持单位，哈尔滨医科大学。已获批准。经费：20万人民币。本人排名第二。2)Sjogren综合症基因表达谱的研究：主持单位，美国明尼苏达大学人类遗传学学院(KLMOSER教授)。本人作为项目的科学顾问。美国国家健康研究院基金项目(2003-2007)。经费：200万美金。已获批准。3)TheCCFCardiovascularSeedGranttoCenterforCardiovascularGenetics.March1,2001-March1,2004($635,070),Co-I.4)NationalHeart,LungandBloodInstituteGenotypingService(2003)MappingGenesforPremature CoronaryArteryDiseases(>500,000genotypes).Co-I.5)TheTechniqueofPatternRecognitionandFeatureExtractionforMappingMulti-geneComplexDiseases,theNationalNaturalScienceFoundationofChina,GrantNo.30170515,01/2002-12/2004(180,000Chinesedollars).Co-I.